Health Problems

A protein called vaccinia-related kinase 1 may help cancer establish itself in new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina (MUSC) examined a protein called vaccinia-related kinase 1 (VRK1) that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and […]

Health Problems

Theranostic complex with two toxic modules shows high toxicity for tumour cells

Emerging cancer nanotechnology enables targeted delivery of drug payloads to cancer sites with concomitant reduction of side effects due to reduced accumulation in critical organs. This prompts research into nanocarriers of therapeutic cargo and contrast agents, allowing combined cancer therapy and tumour visualization, respectively. Researchers from Lobachevsky University of Nizhny Novgorod, Russia, have implemented such […]

Health Problems

Brain iron on MRI linked to disability in multiple sclerosis

(HealthDay)—Brain iron at quantitative magnetic resonance imaging (MRI) is associated with disability in multiple sclerosis (MS), according to a study recently published in Radiology. Robert Zivadinov, M.D., Ph.D., from the University at Buffalo in New York, and colleagues conducted a prospective study between March 2009 and November 2013 involving 600 participants with MS (452 with […]

Health Problems

Challenge continues in developing effective drug treatment for Alzheimer’s disease

The results of a large-scale international study involving the treatment of Alzheimer’s disease, which was led and coordinated by researchers at Trinity College Dublin, have just been published this week in a major medical journal, PLOS Medicine. Alzheimer’s disease, the commonest form of dementia, currently affects approximately 34 million people worldwide, with 10.5 million people […]

Health Problems

Results from the ULTIMATE trial reported

September 24, 2018—The first study designed to determine the benefits of intravascular ultrasound (IVUS) guidance over angiography guidance during drug-eluting stent (DES) implantation in all-comer patients found that IVUS improved clinical outcomes by lowering the rate of target vessel failure at one year. Findings from the ULTIMATE trial were reported today at the 30th annual […]

Health Problems

Cumbersome blood cancer treatment can be postponed

It’s possible to postpone the introduction of blood transfusions for an average of 17 months for patients with the low-risk variant of MDS blood cancer, provided they are given erythropoiesis-stimulating agents (ESA), which stimulate the body to produce red blood cells, according to a dissertation at Sahlgrenska Academy, Sweden. “Traditional treatment has not called for […]

Health Problems

Fear and anger as cholera strikes again in Zimbabwe

Sixty-year-old Emma Zhakata winces, struggling to hold back tears as she relates how her husband, one of 32 cholera victims in Zimbabwe, died within hours of falling ill. She never suspected her 69-year-old husband, Wonder Zhakata, would die suddenly after complaining that he felt weak and was suffering stomach pain. After she rushed her husband […]

Health Problems

New test procedure accelerates the diagnosis of multi-resistant hospital pathogens

A team of researchers at the University of Cologne’s Faculty of Medicine and the German Center for Infection Research (DZIF) has achieved a scientific breakthrough in the accelerated diagnosis of multi-resistant hospital pathogens. Using a novel immunochromatographic method, the researchers detected bacteria that are resistant to the antibiotic group carbapenemes within 20 to 45 minutes […]