Health Problems

Building a better brain-in-a-dish, faster and cheaper

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells. Experimental studies of developing human brain function are limited. Research involving live embryonic subjects is constrained […]

Health Problems

Visceral leishmaniasis on the rise in Brazil, study finds

The parasitic disease leishmaniasis is spread to humans through the bites of sandflies, and is endemic in a number of countries, including Brazil. Despite control efforts, the incidence of visceral leishmaniasis—the most severe form of the disease—rose in Brazil between 1990 and 2016, researchers have reported in PLOS Neglected Tropical Diseases. Leishmaniasis can be classified […]

Health Problems

Brain function impacts how experiences contribute to depression

A study in adolescent girls reports that recent life events impact depressive symptoms differently, depending on how the brain responds to winning and losing. A strong brain response to winning boosted the beneficial impact of positive experiences on symptoms, whereas a strong response to losing enhanced the detrimental impact of negative experiences on symptoms. The […]

Health Problems

Gender identities disrupted—and reinforced

New Northwestern University research analyzing the ways children’s gender narratives reinforce or disrupt gender inequality found that older children—and girls—are more likely to tell alternative narratives that disrupted the gender status quo. In the study, a racially diverse group of more than 230 children, ages 7 to 12 years old, told four types of narratives […]

Health Problems

The paradox of ‘suicide in happy places’ seems not to exist

Several years ago, a research paper made headlines by finding that the happiest states in the United States also had the highest suicide rates. This seemingly paradoxical conclusion caught the attention of a trio of researchers from the University of Colorado Boulder and University of California Irvine for a different reason: could there be more […]

Health Problems

Criminal behavior linked to thinking about risk, study finds

A new study shows a difference between how risk is cognitively processed by self-reported law-abiding citizens and self-reported lawbreakers, allowing researchers to better view and understand the criminal mind. Along with her team, Valerie Reyna, Lois and Melvin Tukman Professor of Human Development and director of the Cornell University Magnetic Resonance Imaging Facility, examined neurological […]

Health Problems

Researchers find disrupted functional connectivity in cerebellum of adults with HF-ASD

A new study using an unbiased, whole-brain data-driven approach to assess the resting-state functional connectome in young adults with high-functioning autism spectrum disorder (HF-ASD) found two clusters of abnormal connectivity in the cerebellum. This finding, which supports a crucial role for the cerebellum in ASD and highlights the cerebellum as a potential therapeutic and diagnostic […]