Health Problems

Study of tick-borne disease dynamics could thwart future outbreaks

The Centers for Disease Control and Prevention (CDC) released a report earlier this year on the increase of tick-, flea- and mosquito-borne illnesses in the United States, but don’t panic. Kurt Vandegrift, assistant research professor of biology at Penn State, works on emerging infectious diseases, and his lab studies ticks. Vandegrift’s lab is part of a National […]

Health Problems

Study finds greater public awareness still needed about dementia

Common beliefs and misconceptions in the community about dementia are still proving obstacles to treatment despite a rise in public awareness campaigns, an Australian study has found. Researchers from Flinders University in South Australia pooled the results of 32 dementia surveys from around the world published between 2012 and 2017 and found that public awareness […]

Health Problems

Injection of vasoactive intestinal peptide into the eye improves corneal transplant survival

A new study in the American Journal of Pathology reports for the first time that injection of neuropeptide vasoactive intestinal peptide (VIP) directly into the eye of mice enhanced corneal graft survival. VIP produced other benefits, including acceleration of endothelial wound closure, protection of corneal endothelial cells (CEnCs), and improved corneal graft clarity. If proven […]

Health Problems

Doxorubicin disrupts the immune system to cause heart toxicity

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure. University of Alabama at Birmingham researchers now describe an important contributor to that heart pathology—disruption of the metabolism that […]

Health Problems

Novel vaccine approach proves powerful against Zika virus

A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, new research has found. A team led by researchers at The Ohio State University has developed and tested a vaccine that employs an uncommon two-pronged approach to fighting the virus, which is spread by mosquitos and is most serious for pregnant women […]

Health Problems

New regulator in aggressive breast cancer cells discovered

Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments. Thus, these tumors are unlikely to respond to current therapies. Researchers from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena now identified the protein TRPS1, which is commonly […]

Health Problems

Seeking a culprit behind rise in colon cancer among younger adults

With the incidence of colorectal cancer rising among younger adults, the American Cancer Society has lowered its recommended age for first screening from 50 to 45. Cancer physician and researcher Kimmie Ng of Harvard-affiliated Dana-Farber Cancer Institute was senior author of a recent study linking a low-insulin-load diet—fruits, vegetables, whole grains, and healthy protein and […]

Health Problems

Field test for dog Leishmania exposure evaluated

Dogs infected with Leishmania infantum, a parasite transmitted by the sand fly Phlebotomus perniciosus, are at risk for spreading leishmaniasis infections to humans. A new test, described and evaluated this week in PLOS Neglected Tropical Diseases, provides an easier-than-ever way to test dogs for exposure to P. perniciosus sand flies, and could be used in […]

Health Problems

TGFB1 mutation ups radiation-induced breast fibrosis risk

(HealthDay)—The C-509T allele in the promoter region of transforming growth factor β (TGFB1) is associated with radiation-induced breast fibrosis risk among patients with early-stage breast cancer, according to study published online July 19 in JAMA Oncology. Aaron J. Grossberg, M.D., Ph.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined […]