Health Problems

Breaking down pathological protein aggregates

ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson’s and other neurodegenerative diseases. This new finding might provide the basis for new therapeutic approaches. Aggregates of the protein alpha-synuclein in the nerve cells of the brain play a key […]

Health Problems

Identification of potential target protein aggregates for treating Alzheimer’s

The aggregation of alpha-synuclein proteins in Parkinson’s disease and tau proteins in Alzheimer’s disease is intimately linked to the progression of these neurodegenerative diseases. These aggregates propagate from one neuronal cell to another, attaching themselves to the cells. They multiply during this propagation. It has already been shown that the propagation and amplification of these […]