Health News

Eyes of Creutzfeldt-Jakob disease patients show evidence of prions

By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. But, in a new study, researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco, report finding tell-tale evidence of the condition’s infectious agent in the […]

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Losing control of gene activity in Alzheimer’s disease

Pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer’s disease and might help identify effective treatments in the future. An international research team led by scientists at the University of Exeter and the University of Essex have uncovered a link between indicators of gene activity and […]

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Modifiable dementia risk factor in older adults identified

For older adults, it may seem as though the die is already cast regarding their odds of developing dementia, but new research from the University of Pittsburgh has identified a dementia risk factor among older adults that should be modifiable even well into old age. The study, which draws on data collected from following hundreds […]

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Strategic plan to address tuberculosis research

Tuberculosis (TB) is the leading infectious cause of death worldwide, killing roughly 1.6 million people in 2017. In the past 200 years, TB claimed the lives of more than one billion people — more deaths than from malaria, influenza, smallpox, HIV/AIDS, cholera and plague combined. Recently, the global health community has strengthened its efforts and […]

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Dementia symptoms peak in winter and spring, study finds

Adults both with and without Alzheimer’s disease have better cognition skills in the late summer and early fall than in the winter and spring, according to a new study published this week in PLOS Medicine by Andrew Lim of Sunnybrook Health Sciences Centre and the University of Toronto, Canada, and colleagues. There have been few […]

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Study provides 10-year risk estimates for dementia, which may help with prevention in high-risk individuals who potentially could benefit from early targeted prevention

A Danish study provides 10-year absolute risk estimates for dementia specific to age, sex and common variation in the APOE gene, which may help identify high-risk individuals who potentially could benefit from early targeted prevention. The study is published in CMAJ (Canadian Medical Association Journal). Dementia is a major cause of disability in older adults […]

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New mechanism for how ALS disease evolves

A mechanism for how the disease amyotrophic lateral sclerosis, or ALS, evolves has been discovered at Umeå University, Sweden. The discovery concerns how proteins with a defect structure spread the deformation to other proteins, according to results in a new thesis. The discovery can open up for novel pharmaceutical developments in the future. “We’ve been […]

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Misfolded proteins serve as ‘inherited memory’ of toxic insults

Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander […]