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Fortis Life Sciences has completed its acquisition of nanoComposix, a premiere nanomaterials company focused on solutions for assay development and diagnostics. Since 2004, nanoComposix has built one of the most comprehensive nanomaterials portfolios in the industry. nanoComposix’s nanomaterials are used in a wide array of Life Sciences applications, including drug delivery, diagnostics and imaging, as […]
A new study led by Hans-Martin Jäck of the Friedrich-Alexander University Erlangen-Nuremberg in Germany engineered clusters of neutralizing monoclonal antibodies using a transgenic mouse model. A unique characteristic for the antibodies was the different ways it bound to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the overall reduction in the viral spread for […]
In general, thermal shift assays can be applied to understand the thermal stabilization that proteins undergo when binding to a ligand. Thermal shift assays have been used in the past to understand proteins and their interactions, often with a focus on drug development. The cellular thermal shift assay (CETSA) takes this a step further by […]
Multiplex immunoassays and enzyme-linked immunosorbent assays (ELISA) are used to determine and analyze the presence of an analyte in a sample through the binding of complimentary antigen-antibody pairs. Multiplex immunoassays are useful in cases of limited sample volume or time. molekuul_be | Shutterstock Multiplex immunoassays can be differentiated by the surface to which the antigens […]
Skip to: What are tumorspheres? Tumorsphere formation assay Technical notes on tumorsphere cultivation What are the types of cancer stem cell (CSC) tumorspheres? Tumorspheres for screening anti-CSC drugs What is the future of tumorspheres? What are tumorspheres? Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, […]
Antimalarial drugs appear to follow a typical pattern, with early effectiveness eventually limited by the emergence of drug resistance. A report in the Journal of Molecular Diagnostics describes a new assay using whole blood that simplifies the genetic analysis of malarial parasites by completely eliminating processing steps. This provides rapid access to critical information associated […]
A new diagnostic test developed at A*STAR is helping researchers around the world identify gene mutations that put people at risk of severe eczema and other chronic skin diseases. The skin’s outer layer forms a protective barrier against the external environment, thanks to a gene called FLG. People lacking a functional copy of this gene, […]
Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas. Identification of these translocations helps establish a correct diagnosis and guides treatment. A report in the Journal of Molecular Diagnostics describes a new assay, anchored […]