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Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
Researchers at the University of Massachusetts Amherst have identified a single-measure biomarker in sperm mitochondrial DNA that may predict male reproductive health and pregnancy success. The discovery applies not just to couples seeking care for infertility but also for the general population. This biomarker could become a more accurate predictor of male infertility than semen […]
The majority of women who undergo surgery for suspected ovarian cancer do not have cancer. A novel blood test developed by researchers at Uppsala University and the Sahlgrenska Academy, University of Gothenburg, now offers the possibility of more precise diagnostics without the need for surgery. This could lead to a reduction in unnecessary surgery and […]
Researchers from the University of Alabama at Birmingham Department of Ophthalmology and Visual Sciences, along with collaborators from the University of Iowa, have discovered a genetic biomarker that is associated with age-related macular degeneration and delayed rod-mediated dark adaptation—the first visual function for incident AMD in older adults with normal macular health and early AMD. […]
A biomarker for multiple sclerosis that could be an early warning for the disease has shown promise in both human and animal testing. Researchers at Purdue University and the Indiana University School of Medicine found that acrolein, a molecule previously suspected as a metabolic waste product that accumulates in people with certain neurological disorders such […]
Cancer patients are known to have an increased risk of thrombosis. As part of the CATS study, MedUni Vienna researchers have now investigated a correlation between an activated immune system in cancer patients and their risk of thrombosis. It was found that citrullinated histone 3, known as “H3Cit”, a protein released into the blood by […]
People living with mental health disorders who benefit from medication may try several types before finding a solution that helps manage their symptoms. But what if a simple blood test could help doctors understand what medication might work best for patients at the start of their treatment? That’s an idea gaining traction and the focus […]