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Doctors at The Ohio State University Wexner Medical Center and College of Medicine are pioneering the use of primary targeted muscle reinnervation (TMR) to prevent or reduce debilitating phantom limb and stump pain in amputees. Losing a limb due to trauma, cancer, or poor circulation can result in phantom limb and stump pain in upwards […]
Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified gene recombination in neurons that produces thousands of new gene variants within Alzheimer’s disease brains. The study, published today in Nature, reveals for the first time how the Alzheimer’s-linked gene, APP, is recombined by using the same type of enzyme found in HIV. Using […]
Pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer’s disease and might help identify effective treatments in the future. An international research team led by scientists at the University of Exeter and the University of Essex have uncovered a link between indicators of gene activity and […]
A simple test taken within a week of a stroke may help predict how well people will have recovered up to three years later, according to a study published in the October 17, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. “We found that this test, which takes less […]
When medical marijuana is taken for chronic nerve pain, it may provide pain relief by reducing connections between the areas of the brain that process emotions and sensory signals, according to a study published in the September 5, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked […]
A mechanism for how the disease amyotrophic lateral sclerosis, or ALS, evolves has been discovered at Umeå University, Sweden. The discovery concerns how proteins with a defect structure spread the deformation to other proteins, according to results in a new thesis. The discovery can open up for novel pharmaceutical developments in the future. “We’ve been […]
Men respond to their spouse’s illness just as much as women do and as a result are better caregivers in later life than previous research suggests, according to a new Oxford University collaboration. The study, published in Journals of Gerontology, Series B, is good news for our increasingly stretched adult care services, which have become […]
A new study has shown that use of peripheral nerve blocks in the treatment of Trigeminal Neuralgia (TGN) may produce long-term pain relief. TGN is a condition involving sudden episodes of severe facial pain that significantly reduces quality of life in those affected. When medication fails to control the pain, some patients turn to invasive […]
Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson’s disease, according to new research from Rice University. “Inflammation and fatigue in early, untreated Parkinson’s disease” will appear in an upcoming edition of Acta Neurologica Scandinavica. It is one of the first studies to link […]
Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer’s disease and type 2 diabetes are not yet available. Scientists at the Technical University of Munich (TUM) have now come a little bit closer to a solution: They have described a new class of designed macrocyclic peptides that are highly potent inhibitors of amyloid […]