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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that they could reengineer adipocytes—fat cells that feed fatty acids energy needed to promote tumor growth and metastasis—to reverse […]
In a current paper published in the journal Nature, Heidelberg-based researchers and physicians describe how neurons in the brain establish contact with aggressive glioblastomas and thus promote tumor growth / New tumor activation mechanism provides starting points for clinical trials Neurons transmit their signals to each other via synapses, fine cell projections with terminals that […]
Nearly 15 million babies are born prematurely, or before 37 weeks of pregnancy, around the world each year. When born too early, a baby’s immature respiratory center in the brain often fails to signal it to breathe, resulting in low oxygen levels, or hypoxia, in the brain. Research published in the Journal of Neuroscience shows […]
Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or after puberty. The majority are benign. Malignant germ cell tumors most frequently appear in the testicle of adolescent and young adult men. Fortunately, […]
Cancer cells can adapt and develop resistance to chemotherapy drugs, making it difficult to eradicate tumors. A new study led by investigators from Brigham and Women’s Hospital suggests that a combination of three drugs, including a new class of glucose-6-phosphate dehydrogenase inhibitors, could overcome cross-therapy resistance. The results of the study are published today in […]
A team of Duke researchers has discovered that cells lining the gut of zebrafish—and probably humans too—have a remarkable defense mechanism when faced with certain kinds of toxins: they hit the eject button. “The gut has the challenging job of handling all the chemicals that we consume or produce, and some of those chemicals can […]
A research team at the University of California, Riverside, has found that electronic cigarettes, often targeted to youth and pregnant women, produce a stress response in neural stem cells, which are critical cells in the brain. Present throughout life, stem cells become specialized cells with more specific functions, such as brain cells, blood cells, or […]
In stunning images captured under the microscope for the first time, the neurons were found in praying mantises. The work is published in Nature Communications today. In a specially-designed insect cinema, the mantises were fitted with 3-D glasses and shown 3-D movies of simulated bugs while their brain activity was monitored. When the image of […]
Current anti-cancer drugs can be quite effective but too often, tumors are not fought off completely and end up returning. A recent study published in The FASEB Journal provides the first evidence that some cancer cells evade therapy by switching over to alternative molecular mechanisms that are not affected by existing anti-cancer treatments. A research […]
Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear. Now, researchers at the Stanford University School of Medicine have identified a specific set of brain cells that are particularly susceptible to harm from low oxygen exposure […]