Health Problems

Kidney cancer study uncovers new subtypes and clues to better diagnosis and treatment

The researchers used the most advanced genomic and proteomic technologies available to tease out their proteogenomic characteristics, defined as genetic makeup (genomics), chemical modifications to DNA (epigenomics), messenger RNA located in cells that serves as template to make proteins (transcriptomics), and proteins (proteomics) and their modification by phosphate group (phosphoproteomics), a modification known to regulate […]

Health Problems

Clues to building a better herpes vaccine

Efforts to develop an effective vaccine for genital herpes, a common sexually transmitted disease, have largely failed. In a new study published in Nature, Yale researchers explore why, and their findings could lead to a better vaccine. Senior investigator Akiko Iwasaki and her colleagues conducted several experiments in mice vaccinated against the herpes simplex virus […]

Personal Health

Rare genetic change provides clues to pancreas development

Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. The study from the Wellcome Sanger Institute, the University of Exeter and collaborators also identified a previously unexpected pathway involved in the development of the human pancreas, and confirmed this in mice. Understanding […]

Health Problems

Hippocampus yields clues to treatment strategies for cognitive deficits in multiple sclerosis

A recent article by a team of international experts on multiple sclerosis (MS) underscores the importance of expanding the knowledge base about the hippocampus in order to better understand the genesis of cognitive deficits and develop new treatment strategies. The article, “The hippocampus in multiple sclerosis”, was published in The Lancet Neurology 2018;17:918-926. The burgeoning […]