Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases. Much less genetic engineering has been devoted to Culex genus mosquitoes, which spread devastating […]
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First CRISPR study inside the body to start in US
Patients are about to be enrolled in the first study to test a gene-editing technique known as CRISPR inside the body to try to cure an inherited form of blindness. People with the disease have healthy eyes but lack a gene that converts light into signals to the brain that enable sight. The experimental treatment […]
Single CRISPR treatment provides long-term benefits in mice
Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease—Duchenne muscular dystrophy (DMD)—for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. The study appears online on February 18 in the journal Nature Medicine. In […]
CRISPR Gene Editing May Be Doing More Damage Than Scientists Thought
Like a molecular ninja, the genome-editing tool CRISPR-Cas9 slices through ultraspecific segments of DNA to cut out unwanted bits of genetic code. It's a precise and promising method of genetic editing that's widely used in scientific research. And scientists hope it could one day be used to selectively remove genes that result in medical problems […]