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Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. Scientists at Cincinnati Children’s Hospital Medical Center report in the American Journal of Respiratory and Critical […]
Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain’s complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette of protein tools. A multidisciplinary team of 14 researchers from the Howard Hughes Medical Institute’s Janelia Research Campus and other institutions […]
By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Yale researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them. Biofilms form when bacterial cells gather and […]
A defective gene causes thick, sticky mucus to build up in the lungs of patients with cystic fibrosis (CF). There, it traps bacteria, causing patients to develop frequent lung infections that progressively damage these vital organs and impair patients’ ability to breathe. Most patients with this progressive genetic disorder die by the fourth decade of […]
In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than […]