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Once in Berghain to celebrate – that was the dream of Jenifer and Carlo from Culver City, Los Angeles. For the couple the night of partying, the highlight of your multi-day Berlin trip. But the evening in the summer of 2017, ending in a tragedy. The 30-year-old lawyer takes two Ecstasy pills and dies hours […]
A combination of two immunotherapy drugs, ipilimumab and nivolumab, has stopped or reversed the progression of advanced melanoma for five years or more in one in two patients, according to a study led by The Royal Marsden NHS Foundation Trust. Just 10 years ago, only 1 in 20 patients with advanced melanoma would survive for […]
The first signs of Huntington’s, an inherited disease that slowly deteriorates bodies and minds, don’t typically surface until middle age. But new findings suggest that something in the brain might be amiss long before symptoms arise, and earlier than has ever been observed. Using a new technology, Rockefeller scientists were able to trace the causes […]
Content warning: this article discusses drug addiction I’ll never forget the first time I took codeine. It gave me a warm feeling, as if I was floating on a pink fluffy cloud, and all my troubles and worries melted away. This week, Public Health England announced fears that a large number of people who are […]
Cancer cells can adapt and develop resistance to chemotherapy drugs, making it difficult to eradicate tumors. A new study led by investigators from Brigham and Women’s Hospital suggests that a combination of three drugs, including a new class of glucose-6-phosphate dehydrogenase inhibitors, could overcome cross-therapy resistance. The results of the study are published today in […]
The use of prescription stimulants by those without medically diagnosed conditions marks a growing trend among young adults—particularly college students seeking a brain boost. But according to a study led by the University of California, Irvine, taking a nonprescribed psychostimulant may slightly improve a person’s short-term focus but impede sleep and mental functions that rely […]
Microdosing psychedelics is a growing trend that involves ingesting very small sub-hallucinogenic amounts of substances like LSD or dried psilocybin-containing mushrooms. We ran a large-scale, pre-registered global research study asking participants to report what they like and dislike about microdosing. The three most commonly reported benefits were: improved mood, increased focus and enhanced creativity. The […]
Statins, the most commonly used effective lipid-lowering drugs, are significantly underutilized to treat lipid abnormalities in patients with and at risk for atherosclerotic cardiovascular disease (ASCVD), according to a retrospective study of more than 280,000 patients in Alberta, Canada. Investigators report in the Canadian Journal of Cardiology, published by Elsevier, that only two-thirds of these […]
For grandma and grandpa it is a great pleasure to spend time with her grandchildren. What, according to a new survey, however, too little is thought of that: medications must be in child-proof places kept in order to minimize the risk of poisoning. More than 80 per cent of grandparents say they store their medications […]
Antimalarial drugs appear to follow a typical pattern, with early effectiveness eventually limited by the emergence of drug resistance. A report in the Journal of Molecular Diagnostics describes a new assay using whole blood that simplifies the genetic analysis of malarial parasites by completely eliminating processing steps. This provides rapid access to critical information associated […]