Personal Health

Team plucks needle from genomic haystack, finding essential transcription factor binding sites

Using CRISPR/Cas9 knockout screens a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer cells, plucking useful needles from a massive genomic haystack that contains millions of transcription factor binding sites. They found that essential FOXA1 binding sites act […]

Health Problems

Connecticut sees first death this year from mosquito-borne EEE

A Connecticut resident has died from eastern equine encephalitis (EEE), the first such death in the state since 2013, health officials report. In addition, another person in the state has contracted the infection, as an outbreak grows. It has been an unusually active year for EEE, with cases reported in several northeast states. In Massachusetts, […]