Personal Health

A case against a moratorium on germline gene editing

Should researchers put the brakes on genetically engineering babies? Leading scientists and ethicists recently called for a moratorium on clinical applications of germline gene editing: inheritable alterations to the DNA of embryos to improve kids’ health or other features – or just “gene editing,” for short. This declaration was prompted in part by the birth […]

Health Problems

Influenza A deliberately enhances levels of the human p53 protein to reduce anti-viral gene and protein expression

Genome editing technology is helping A*STAR scientists unravel how the Influenza A virus (IAV) exploits human anti-viral responses. IAV remains a key challenge for global health resources, not least because of wide variations in symptom severity experienced by different people, even when they are infected by the same strain. This implies that there are host […]

Health News

Does Dyslexia Gene Protect Against Concussions?

FRIDAY, Oct. 26, 2018 — Athletes may be less likely to suffer concussions if they carry a gene linked to the learning disorder dyslexia, a new study suggests. Researchers looked at the concussion history of 87 football players at Penn State University. They also checked the players for certain genes. The findings suggest that “genotype […]

Health Problems

Advancing gene therapy for skin cancer

One of the deadliest skin cancers, melanoma may be caused by overexposure to ultraviolet radiation from the sun or artificial sources such as tanning beds and sunlamps. The Melanoma Network of Canada reports that lifetime risk for developing melanoma has increased to one in 63 people today—up from one in 1,500 in the 1930s. “It […]

Personal Health

A single missing gene leads to miscarriage

A single gene from the mother plays such a crucial role in the development of the placenta that its dysfunction leads to miscarriages. Researchers from the Medical Faculty of Ruhr-Universität Bochum (RUB) have observed this in so-called knockout mice that were specifically modified for this purpose. These mice lack the gene for the transcription factor […]

Health Problems

Gene plays critical role in noise-induced deafness

In experiments using mice, a team of UC San Francisco researchers has discovered a gene that plays an essential role in noise-induced deafness. Remarkably, by administering an experimental chemical—identified in a separate UCSF lab in 2013—that acts on the pathway linking this gene to hearing loss, they found that they could prevent noise-induced deafness in […]

Health Problems

Gene signature predicts outcome after spinal cord injury

Scientists have determined a gene signature that is linked to the severity of spinal cord injury in animals and humans, according to a study in the open-access journal eLife. The discovery of key genes that are switched on or off in response to spinal cord injury could inform the development of biomarkers that predict recovery […]