Health News

Scientists uncover binding secret behind protein ‘superglue’: Mechanism found in Chinese herb helps to create lab-grown enzymes that may speed up drug development

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have pinpointed how a special class of plant-derived enzymes, known as peptide ligases, work to join proteins together. Such binding is an important process in the development of drugs, for example in specifically attaching a chemotherapy drug to an antibody that recognises tumour markers to target cancer […]

Health News

Developing a vaccine against Nipah virus

Nipah virus is a type of RNA virus transmitted from animals to humans. The infection causes severe respiratory illness and symptoms including cough, headache and fever, which can progress into encephalitis, seizure and coma. Currently, there is no approved vaccine against Nipah virus available on the market. In recent years, outbreaks, from bat-to-human or pig-to-human […]

Health News

A new aspect in Plasmodium falciparum life cycle revealed: ‘Express’ sexual conversion: Conversion from the asexual to the sexual phase of the malaria parasite is necessary for its transmission to the mosquito

A study led by the Barcelona Institute for Global Health (ISGlobal) — an institution supported by “la Caixa” Foundation- reveals a new mechanism by which the malaria parasite Plasmodium falciparum converts from its asexual to its sexual form, which can be transmitted to the mosquito. The results, published in Nature Microbiology, provide important information on […]

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Strategic plan to address tuberculosis research

Tuberculosis (TB) is the leading infectious cause of death worldwide, killing roughly 1.6 million people in 2017. In the past 200 years, TB claimed the lives of more than one billion people — more deaths than from malaria, influenza, smallpox, HIV/AIDS, cholera and plague combined. Recently, the global health community has strengthened its efforts and […]

Health News

Whole blood test for toxoplasmosis is sensitive, specific

Transmission of toxoplasmosis from mother to fetus can lead to severe congenital problems and fetal death, and tests for the parasitic infection during pregnancy are critical. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed the efficacy of a low-cost whole blood test for toxoplasmosis. Toxoplasmosis results from infection with the Toxoplasma gondii parasite, […]