Health Problems

New drug brings unexpected hope in targeting cancer cells

An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers. This latest finding, published in the journal Theranostics, was discovered while studying activated platelets in the setting of heart disease and may now […]

Health Problems

Researchers hope to be able to replace dysfunctional brain cells

A new study by researchers at Karolinska Institutet supports the theory that replacement of dysfunctional immune cells in the brain has therapeutic potential for neurodegenerative diseases like ALS and Alzheimer’s disease. The study, which involved repopulating the brain with new immune cells in an experimental disease model, is published in Nature Communications. Macrophages are immune […]

Health Problems

Old drug, new hope for pediatric brain cancer

Some drugs for heart disease might also work against brain cancer, according to an analysis by researchers from the Jackson Laboratory (JAX), Connecticut Children’s Medical Center (CCMC), and UConn Health. The researchers used a new approach to identify five heart medicines that might also be effective at fighting the most common type of childhood brain […]

Health Problems

Tailored drug cocktails offer hope to kids with aggressive brain tumors

UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in which survival has plateaued for decades. In the trial, UCSF […]

Health Problems

Reversing influences of intergenerational stress offers hope for addressing public health

In an effort to help protect children from intergenerational vulnerabilities associated with parental trauma and stress, researchers at the Yerkes National Primate Research Center, Emory University, have shown for the first time in an animal model it is possible to reverse influences of parental stress by exposing parents to behavioral interventions following their own exposure […]