Health Problems

New model mimics human tumors for accurate testing of cancer drugs

Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]

Health Problems

Scientists grow human esophagus in lab

Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. Published in the journal Cell Stem Cell the study is the latest advancement from researchers at the Cincinnati Children’s Center for Stem Cell and Organoid Medicine (CuSTOM). The center is developing new […]

Health News

Is Evolution of the Human Brain to Blame for Some Mental Disorders?

THURSDAY, Aug. 9, 2018 — Evolutionary changes in the human brain may be responsible for psychiatric illnesses such as schizophrenia and bipolar disorder, new research suggests. The researchers identified long, noncoding stretches of DNA (called “repeat arrays”) in a gene that governs calcium transport in the brain. Their findings were published Aug. 9 in the […]

Personal Health

Evolutionary changes in the human brain may have led to bipolar disorder and schizophrenia

The same aspects of relatively recent evolutionary changes that make us prone to bad backs and impacted third molars may have generated long, noncoding stretches of DNA that predispose individuals to schizophrenia, bipolar disorder, and other neuropsychiatric diseases. A study publishing August 9 in the American Journal of Human Genetics identifies an unusually lengthy array […]