Health News

Doctors issue caution over missed cancer diagnoses tied to immune disorder: Study shows HLH diagnosis may obscure underlying malignancies

Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs — often causing death — doctors frequently […]

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Heart attack: Substitute muscle thanks to stem cells

Myocardial infarction — commonly known as a heart attack — is still one of the main causes of death. According to the Federal Statistical Office, more than 49,00 people died of its consequences. And yet the mortality after heart attack has greatly decreased over the past decades: As compared to the early 1990s, it has […]

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Farewell flat biology: Tackling infectious disease using 3-D tissue engineering

In a new invited review article, ASU Biodesign microbiologists and tissue engineers Cheryl Nickerson, Jennifer Barrila and colleagues discuss the development and application of three-dimensional (3-D) tissue culture models as they pertain to infectious disease. They describe these models as predictive pre-clinical platforms to study host-pathogen interactions, infectious disease mechanisms, and antimicrobial drug development. The […]

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Misfolded proteins serve as ‘inherited memory’ of toxic insults

Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander […]

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Maternal depression may alter stress and immune markers in children

New research suggests that depression in women may affect their children’s stress and physical well-being throughout life. For the Depression & Anxiety study, researchers followed 125 children from birth to 10 years. At 10 years, mothers’ and children’s cortisol (CT) and secretory immunoglobulin (s-IgA) — markers of stress and the immune system — were measured, […]

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Autoimmunity plays role in development of COPD

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a study led by Georgia State University and Vanderbilt University Medical Center that analyzed human genome information stored in Vanderbilt’s DNA biobank. COPD is a group of diseases that cause airflow blockage and breathing-related problems. COPD, which includes emphysema and […]