Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled “GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma” in Science Signaling. The KEAP1-NRF2 pathway plays a key role in cancer prevention and protective cellular responses to oxidative and electrophilic stress. In normal and premalignant tissues […]
Glimmers of hope for immunity in survivors of mild COVID-19
Glimmers of hope for COVID-19 immunity: Studies suggest that even people who had mild infections develop multiple cellular defenses against catching coronavirus again Coronavirus antibody levels fall quickly in people who had only mild infections Recent research found that other immune components – T and B cells – in mild infection survivors ‘remember’ coronavirus and […]
How You Can Get Involved in Clear the Shelters 2020!
Every year we participate in Clear the Shelters, an annual adoption event that encourages people nationwide to open their hearts to rescue animals and increase adoptions. While this adoption event is normally celebrated on a single day, this year we’ll be celebrating Clear the Shelters for the entire month of August! During this month, we’re […]
New experimental coronavirus vaccine prevented severe disease in mice
New experimental coronavirus vaccine prevented severe disease in mice after two doses of the jab boosted their antibody levels 90-fold Researchers genetically modified vesicular stomatitis virus (VSV), which causes a mild illness in livestock, to become a vaccine The team took out a gene from VSV and inserted the spike protein from the coronavirus, which […]
1 in 10 women are affected by endometriosis. So why does it take so long to diagnose?
Endometriosis is a debilitating, chronic condition that affects 1 in 10 women worldwide. It occurs when tissue which has similar properties to the womb lining, ends up in the body and attaches to organs, forming a patch of tissue called a lesion. The condition can cause chronic pelvic pain, bowel and bladder dysfunction, and pain […]
Novel approach reduces SCA1 symptoms in animal model
Research has shown that a mutation in the ATAXIN-1 gene leads to accumulation of Ataxin-1 (ATXN1) protein in brain cells and is the root cause of a rare genetic neurodegenerative disease known as spinocerebellar ataxia type 1 (SCA1). How healthy cells maintain a precise level of ATXN1 has remained a mystery, but now a study […]
The next coronavirus may already be circulating in bats, study suggests
While the exact origin of the coronavirus remains murky, scientists have been racing to determine how it jumped from animals to humans so they can prevent another pandemic. The next one could just be a matter of time, a study published recently suggests. The authors said a virus with similar ability to infect humans may […]
How we found coronavirus in a cat
Since the outset of the coronavirus pandemic, the potential role of animals in catching and spreading the disease has been closely examined by scientists. This is because the virus that causes COVID-19 belongs to the family of coronaviruses that cause disease in a variety of mammals. The evidence suggests that this virus arose in bats […]
PPE unmasked: why health-care workers in Australia are inadequately protected against coronavirus
In Victoria, more than 1,100 health-care workers have now been infected with SARS-CoV-2, the coronavirus that causes COVID-19. Some 11% of active cases are workers in the health-care sector. Health-care workers are reported to be among those fighting for life in Victorian intensive care units. While we don’t know what proportion of the Victorian health-care […]
Short video may lower parent interest in antibiotics for child
(HealthDay)—A 90-second animated video can reduce parents’ interest in receiving antibiotics for their child’s respiratory infection, according to a study published online June 15 in The Journal of Pediatrics. Kathy Goggin, Ph.D., from Children’s Mercy Hospitals and Clinics in Kansas City, Missouri, and colleagues assessed the impact of a 90-second animated video on parents’ interest […]