Health News

New therapy for aggressive blood cancer discovered

Researchers at the Vetmeduni Vienna and the Ludwig Boltzmann Institute for Cancer Research have identified a new therapeutic strategy for Acute Myeloid Leukemia (AML), the most common form of acute leukemia. They found that the activity of the mutated oncogenic protein C/EBPα is dependent on a functional epigenetic helper, the MLL1 histone methyltransferase complex. Laboratory […]

Health News

Cancer has a biological clock and this drug may keep it from ticking: A promising drug slows cancer’s circadian clock, halts its spread

A new drug shows potential to halt cancer cells’ growth by stunting the cells’ biological clock. The findings from scientists at the USC Michelson Center for Convergent Bioscience and Nagoya University’s Institute of Transformative BioMolecules (ITbM) advance a burgeoning area of research: turning the body’s circadian rhythms against cancer. Their study, conducted on human kidney […]

Health Problems

New treatment approach for leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia. The gene causes white blood cells to become leukemia cells that reproduce out of control. Earlier studies by the research group of Veronika Sexl at Vetmeduni Vienna had already […]

Health News

Test for esophageal cancer could save millions of lives: A tiny capsule, a string and a 2-centimeter sponge are the future of screening for deadly disease

Cancer of the esophagus claims more than 400,000 lives around the world each year. With no efficient, reliable method of screening for the disease, by the time symptoms become apparent, it’s often too late to save the patient. A Johns Hopkins researcher who has devoted his career to the detection and prevention of esophageal cancer […]

Health News

Breast cancer cells become invasive by changing their identity

Researchers from Karolinska Institutet in Sweden have identified a protein that determines the identity and invasive properties of breast cancer cells. The finding could lead to the development of new therapeutic and diagnostic strategies to target breast cancer invasion and metastasis. The study is published in the scientific journal Cancer Research. Cancer cell invasion of […]

Health News

Imaging collaboration sheds new light on cancer growth

Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumour expansion. The findings could help researchers predict how cancer cells respond to chemotherapy and improve our understanding of how cancer evolves. Published in the journal Cell Cycle, the […]

Health News

Doctors issue caution over missed cancer diagnoses tied to immune disorder: Study shows HLH diagnosis may obscure underlying malignancies

Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs — often causing death — doctors frequently […]

Health Problems

Trial participation among factors influencing risk of relapse in AYA leukemia patients

Adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) were significantly more likely to relapse than pediatric ALL patients, and factors including lower clinical trial enrollment and shorter duration of therapy were associated with relapse. The study is published in the Cancer Epidemiology, Biomarkers & Prevention, by Julie A. Wolfson, MD, MSHS, assistant […]

Health News

Strategies to protect bone health in hematologic stem cell transplant recipients

Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in such transplantation techniques and supportive care measures, has led to greater numbers of long-term HSCT survivors. Consequently, an increasing patient population is impacted by […]