Health News

Scientists developing way to help premature babies breathe easier: Study points to possible cell therapy for bronchopulmonary dysplasia

Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. Scientists at Cincinnati Children’s Hospital Medical Center report in the American Journal of Respiratory and Critical […]

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Molecular chatter makes for a ‘hot tumor’

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells. “We show that two key chemokines, CCL5 and CXCL9, are universally implicated in T cell infiltration across all solid tumors,” said George […]

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Scientists uncover binding secret behind protein ‘superglue’: Mechanism found in Chinese herb helps to create lab-grown enzymes that may speed up drug development

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have pinpointed how a special class of plant-derived enzymes, known as peptide ligases, work to join proteins together. Such binding is an important process in the development of drugs, for example in specifically attaching a chemotherapy drug to an antibody that recognises tumour markers to target cancer […]

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Protein that hinders advancement of prostate cancer identified

Researchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer (CRPC). Under the direction of BUSM’s Gerald V. Denis PhD, researchers have long studied a family of three closely related proteins, called BET bromodomain proteins, composed of […]

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New ways to generate stem cells more efficiently

Induced pluripotent stem (iPS) cells are among the most important tools in modern biomedical research, leading to new and promising possibilities in precision medicine. To create them requires transforming a cell of one type, such as skin, into something of a blank slate, so it has the potential to become virtually any other kind of […]

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Fishing for cures: New zebrafish model identifies drugs that kill pediatric cancer cells

A new animal model developed by Massachusetts General Hospital (MGH) investigators promises to be less expensive, easier to use and to improve personalized therapies for cancers and potentially other diseases. In their paper published online in Cell, the investigators describe using their immunodeficient zebrafish model to visualize drug responses at single-cell resolution in live animals. […]

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Magnetic nanoparticles can ‘burn’ cancer cells: Magnetic hyperthermia is still a highly experimental cancer treatment, but new research shows that the therapy is tunable

Unfortunately, cancer isn’t simply a single disease, and some types, like pancreas, brain or liver tumours, are still difficult to treat with chemotherapy, radiation therapy or surgery, leading to low survival rates for patients. Thankfully, new therapies are emerging, like therapeutic hyperthermia, which heats tumours by firing nanoparticles into tumour cells. In a new study […]