besthealtharticle.com
Mayo Clinic researchers and their collaborators have shown that when senescent cells — also known as “zombie cells” — are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear. The findings appear in Aging Cell. Inflammation and dysfunction of fat tissue cause some […]
Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum — a common oral bacteria often implicated in tooth decay — accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports. Why it matters The findings could make it easier to identify and treat more […]
Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. By inducing non-insulin-producing human pancreatic cells to modify their function to produce insulin in a sustainable way, researchers at the University of Geneva (UNIGE), Switzerland, show for the first time that the adaptive capacity of our cells […]
Researchers at the Vetmeduni Vienna and the Ludwig Boltzmann Institute for Cancer Research have identified a new therapeutic strategy for Acute Myeloid Leukemia (AML), the most common form of acute leukemia. They found that the activity of the mutated oncogenic protein C/EBPα is dependent on a functional epigenetic helper, the MLL1 histone methyltransferase complex. Laboratory […]
Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs, which must be able to kill their target cells. Analyzing cell survival is also an important task in fields such as environmental regulation, to test industrial and agricultural chemicals for possible harmful effects on healthy cells. MIT […]
Tissues and organs in the human body are shaped through forces generated by cells, that push and pull, to “sculpt” biological structures. Thanks to a new tool developed at McGill University, scientists will now be able to watch, and map these forces. Christopher Moraes, an assistant professor in McGill’s Department of Chemical Engineering, and colleagues […]
A new drug shows potential to halt cancer cells’ growth by stunting the cells’ biological clock. The findings from scientists at the USC Michelson Center for Convergent Bioscience and Nagoya University’s Institute of Transformative BioMolecules (ITbM) advance a burgeoning area of research: turning the body’s circadian rhythms against cancer. Their study, conducted on human kidney […]
Like planets, the body’s cell surfaces look smooth from a distance but hilly closer up. An article published in Communications Biology describes implications, unknown to date, of the way data from cell surfaces are normally interpreted; i.e. as if they lacked topographic features. When Earth is studied from space, its surface looks smooth, but on […]
Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this new therapy, and an interdisciplinary team of FSU researchers is now a little bit closer to figuring out why. Associate Professor of Statistics Jinfeng Zhang, Professor of […]
Scientists at Kyushu University and Tokyo Institute of Technology in Japan have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture previously unexamined epigenomic information, facilitate biomarker discovery and open new avenues for precision medicine. A collaborative study by researchers […]