Health Problems

New research provides better way to gauge pain in mice

For decades, biomedical researchers have used mouse behavior to study pain, but some researchers have questioned the accuracy of the interpretations of how mice experience pain. Now, Rutgers University-Camden neuroscientist Nathan Fried and colleagues from the University of Pennsylvania have developed a method that can more accurately gauge pain in mice, which could lead researchers […]

Health News

Could better tests help reverse the rise of drug-resistant infections? Modeling study says yes in theory; now comes a reality check

A growing number of infections — such as pneumonia, gonorrhea and tuberculosis — are becoming harder to treat, as bacteria evolve defenses against antibiotics faster than we can develop new drugs to replace them. Duke University game theorist David McAdams says faster, more accurate tests for drug-resistant infections are being developed that could, at least […]

Health News

How a common oral bacteria makes colon cancer more deadly: Findings may help predict aggressive colon cancer and identify new treatment targets

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum — a common oral bacteria often implicated in tooth decay — accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports. Why it matters The findings could make it easier to identify and treat more […]

Health Problems

Altered brain activity patterns of Parkinson’s captured in mice

The tell-tale tremors of Parkinson’s disease emerge from abnormal activity in a brain region crucial for voluntary movement. Using a mouse model of the disease, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) identified unusual patterns of brain activity that appear to underlie its signature symptoms. Parkinson’s disrupts the basal ganglia, […]

Personal Health

Single CRISPR treatment provides long-term benefits in mice

Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease—Duchenne muscular dystrophy (DMD)—for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. The study appears online on February 18 in the journal Nature Medicine. In […]

Health News

Uncovering the evolution of the brain: Scientists compare the development of brain cells between humans and nonhuman primates in a novel way

What makes us human, and where does this mysterious property of “humanness” come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences. Now, researchers from the Salk Institute, in collaboration with researchers from the anthropology department at UC San Diego, have developed a strategy to more easily […]

Health Problems

Common food additives may promote anxiety-related behavior and reduce social behavior in mice, research shows

Food additives known as dietary emulsifiers, commonly found in processed foods to improve texture and extend shelf life, may adversely affect anxiety-related and social behaviors in mice, Georgia State researchers have found. The scientists also observed sex differences in the mice’s behavioral patterns, suggesting that emulsifiers affect the brain via distinct mechanisms in males and […]