Health Problems

New tumor model helps researchers treat pancreatic cancer

Patients diagnosed with pancreatic cancer face a poor prognosis because the tumor forms dense scar-like tissue that is difficult for chemotherapy drugs to penetrate, but a new model may help researchers develop new therapies. “More than 85 percent of pancreatic tumors form this fibrous tissue,” explained Assistant Professor Joshua Reineke of the South Dakota State […]

Health News

Model Identifies Adolescents at Risk for Smoking Initiation

THURSDAY, Oct. 18, 2018 — A novel prognostic tool can be used to accurately identify adolescents at risk for initiating cigarette smoking, according to a study published online Oct. 1 in Pediatrics. Marie-Pierre Sylvestre, Ph.D., from the Université de Montréal, and colleagues used data from the Nicotine Dependence in Teens study. A total of 1,294 […]

Health News

AI model takes us closer to personalised cancer treatments

The ‘holy grail’ of cancer treatment: Scientists take a huge step towards personalised therapies after developing an AI model that predicts how tumours will respond to drugs Could help doctors identify the best treatment and drug dose for each patient The model may be available on the NHS in as little as 10 years time […]

Health Problems

New model mimics human tumors for accurate testing of cancer drugs

Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]

Health Problems

Model estimates mortality in patients waiting for hearts

(HealthDay)—For patients with advanced heart failure who are listed for transplantation, mortality risk is related to adverse events and end-organ dysfunction that vary over time, according to a study published in the Aug. 7 issue of the Journal of the American College of Cardiology. Eugene H. Blackstone, M.D., from the Cleveland Clinic, and colleagues developed […]

Health Problems

Microfluidic system incorporates neuroinflammation into ‘Alzheimer’s in a dish’ model

Building on their development of the first culture system to replicate fully the pathology behind Alzheimer’s disease, a Massachusetts General Hospital (MGH) research team has now produced a system that includes neuroinflammation, the key biological response that leads to the death of brain cells. The investigators describe their system, which incorporates the glial cells that […]