Health Problems

Alternative molecular mechanisms observed in cancer cells

Current anti-cancer drugs can be quite effective but too often, tumors are not fought off completely and end up returning. A recent study published in The FASEB Journal provides the first evidence that some cancer cells evade therapy by switching over to alternative molecular mechanisms that are not affected by existing anti-cancer treatments. A research […]

Personal Health

Scientists catch heartbeat ‘molecular switch’ in action

Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat. In a paper published in the journal Circulation Research, they used this technique to uncover the effects of genetic errors that contribute to […]

Health Problems

Faulty molecular master switch may contribute to AMD

A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have found that interrupting TGF-beta signals to immune cells called microglia causes the cells to enter an activated, inflammatory state. […]

Health News

Molecular link between body weight, early puberty identified

Becoming overweight at a young age can trigger a molecular chain reaction that leads some girls to experience puberty early, according to new research published in Nature Communications. Scientists have discovered a molecular mechanism that leads overweight female rats to have early-onset puberty. “Knowing how nutrition and specific molecules play a role in starting puberty […]