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Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled “GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma” in Science Signaling. The KEAP1-NRF2 pathway plays a key role in cancer prevention and protective cellular responses to oxidative and electrophilic stress. In normal and premalignant tissues […]
New experimental coronavirus vaccine prevented severe disease in mice after two doses of the jab boosted their antibody levels 90-fold Researchers genetically modified vesicular stomatitis virus (VSV), which causes a mild illness in livestock, to become a vaccine The team took out a gene from VSV and inserted the spike protein from the coronavirus, which […]
The loss of a sense of smell is known to be one of the earliest signs of Parkinson’s disease (PD) and can even appear years before the characteristic tremors and loss of motor function are seen. Some scientists believe that olfactory dysfunction may not just be a sign of broader neural damage, but rather may […]
It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to attract cancer? To answer this question, Professor […]
The United States, the country hardest hit by the coronavirus, on Saturday posted 66,528 new cases, a record for a 24-hour period, according to a tally from Johns Hopkins University. The country has now recorded a total of 3,242,073 infections, the Baltimore-based university said in its latest data as of 8:30 pm (0030 GMT Sunday). […]
Credit: CC0 Public Domain New York on Tuesday doubled to 16 the number of US states whose residents must go into quarantine if they visit, Governor Andrew Cuomo said amid surging coronavirus infection rates. Cuomo said visitors from California, Nevada, Georgia, Iowa, Idaho, Louisiana, Mississippi and Tennessee must now quarantine for 14 days if they […]
By studying an individual with an extremely rare brain anomaly that prevents him from seeing certain numbers, Johns Hopkins University researchers provided new evidence that a robust brain response to something like a face or a word does not mean a person is aware of it. The work, set to be published today by Proceedings […]
A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency (SCID). The results of this work was presented Tuesday in the medical journal Blood Advances published by the American Society of Hematology. Routine neonatal screening, although not yet available in Quebec, has led to an increase […]
University of British Columbia (UBC) researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the most common and deadliest form of the disease. The development and validation of the test […]
Prof. Euisik Yoon’s research group has developed a new, faster method to identify cancer stem-like cells (CSCs), which could help improve the effectiveness of cancer treatments. CSCs can seed and develop tumors in metastatic sites, causing cancer to relapse in patients after treatment. They are also generally resistant to chemotherapy and radiotherapy, so therapeutics that […]