Health Problems

Testosterone Replacement Therapy for Men: Risks and Benefits

Skip to: What is Testosterone Replacement Therapy? What are the Benefits of TRT? What are the Risks of TRT? Testosterone plays a vital role in the human body. Its effects increase muscle and bone strength and density, induce hematopoiesis, and drive libido and sexual function. Testicular production of testosterone typically declines with age, which can […]

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Tumorsphere Formulation and Use in Cancer Stem Cell Research

Skip to: What are tumorspheres? Tumorsphere formation assay Technical notes on tumorsphere cultivation What are the types of cancer stem cell (CSC) tumorspheres? Tumorspheres for screening anti-CSC drugs What is the future of tumorspheres? What are tumorspheres? Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, […]

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Pioneering drug that hits prostate cancer's weak spot

Pioneering drug that hits prostate cancer’s weak spot gives hope to men with the incurable disease Olaparib works by interfering with key process that allows tumour cells to repair  Drug already given to women with a specific type of breast and ovarian cancer  Roughly 50,000 men in the UK each year are diagnosed with prostate […]

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Prostate cancer patients could be spared radiotherapy after surgery

Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back Roughly 15,000 men could avoid radiotherapy while undergoing prostate cancer treatment  Research in The Lancet found there was no benefit of the treatment  ‘Radiotherapy need only […]

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Study reveals an inherited origin of prostate cancer in families

Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease. The researchers analyzed the Nashville Familial Prostate Cancer Study (NFPCS), in an investigation comparing men with prostate cancer, […]

Health Problems

Being active reduces risk of prostate cancer

Prostate cancer is the most common cancer in men in the UK , yet we still don’t know all of its causes. The largest ever study to use genetics as a measurement for physical activity to look at its effect on prostate cancer, reveals that being more active reduces the risk of prostate cancer. Over […]

Health Problems

Driver found for more deadly prostate cancer

A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say. BRN4 is mostly expressed in the central nervous system and inner ear, but now scientists have the first evidence it’s amplified and overexpressed in patients […]