Health News

Despite changes to US kidney allocation system, inequality persists

The implementation of a new U.S. kidney transplant allocation system did not solve many of the inequities that low-income and minority kidney disease patients face, Drexel University College of Medicine researchers found in a new study published recently in the journal Clinical Transplantation. The study strengthens the argument that early disease diagnosis and preemptive waitlisting […]

Health Problems

Doxorubicin disrupts the immune system to cause heart toxicity

Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure. University of Alabama at Birmingham researchers now describe an important contributor to that heart pathology—disruption of the metabolism that […]

Health Problems

Microfluidic system incorporates neuroinflammation into ‘Alzheimer’s in a dish’ model

Building on their development of the first culture system to replicate fully the pathology behind Alzheimer’s disease, a Massachusetts General Hospital (MGH) research team has now produced a system that includes neuroinflammation, the key biological response that leads to the death of brain cells. The investigators describe their system, which incorporates the glial cells that […]

Health News

How your immune system promotes friendly gut bacteria

They found that immunoglobulin A (IgA) antibodies released by the gut can alter how bacteria express their genes. This encourages the microorganisms to form communities that work together to defend against disease and safeguard the health of their “host.” Antibodies are involved in the immune response and have long been recognized as fighters of harmful […]