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The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover. Adrian Cadar, Ph.D., and colleagues have now used the microscopy technique FRAP (fluorescence recovery after photobleaching) to study titin dynamics in contracting cardiomyocytes. […]
Would you brush off a serious injury as “just a scratch”? Perhaps you’re the opposite and a stubbed toe is unbearable. Anyone who follows sports will be used to seeing rugby players spending 90 minutes pretending they’re unhurt while the footballer writhes in apparent agony (though that usually happens in the penalty area, strangely enough). […]
Millions of people worldwide are prescribed antipsychotics every year. While these drugs are effective in treating the symptoms of schizophrenia, they can also have significant side-effects, causing weight gain, diabetes and raised cholesterol. These are all risk factors for cardiovascular disease—the biggest killer of people with schizophrenia. However, our latest study found that not all […]
The annual worldwide fitness trends for 2020 survey results have been published and the findings reveal we are becoming savvier and less influenced by fads and gimmicks. The survey of more than 3000 fitness professionals and experts around the world, named wearable tech as the top trend, followed by HIIT; group training; free weights; personal […]
There’s a lot of anxiety about kids and technology these days, and while parents can do things like limit screentime, they can’t fully remove their kids from the 21st century. Whether we like it or not, kids are going to be able to grow up to rely on very advanced computers in their pockets to […]
When it comes to words capable of sending chills down the spine of a pregnant woman, “epidural” is up there with “forceps” and “episiotomy.” But like many things, the reality of an epidural — which involves administering a drug into the space around the spinal cord during labor — isn’t as scary as it sounds. […]
Girl, two, is the only person in the WORLD to have a type of ‘Benjamin Button’ disease as her father reveals he calls her GRANDMA Isla Kilpatrick-Screaton has a unique type of mandibuloacral dysplasia The two-year-old, from Leicester, weighs only 15lbs (7kg) and uses sign language Her condition makes her cells age faster than normal, […]
Exposure to antidepressants during pregnancy and the first weeks of life can alter sensory processing well into adulthood, according to research in mice recently published in eNeuro. Physicians are increasingly prescribing a common antidepressant to their pregnant patients, even though the effect on the fetus isn’t fully known. A working theory of depression implicates the […]
We are not shy about the fact that we completely stan the always-real, always-outspoken Teigen-Legend family. When we heard that supermodel and cookbook author Chrissy Teigen took daughter Luna, 3, to see ballerina Misty Copeland perform in The Nutcracker at the American Ballet Theatre’s production, we just knew there had to be adorable photo evidence […]
With shorter daylight hours, busier than usual schedules and travel to different time zones, the holiday season can disrupt our circadian rhythm and create sleep difficulties—making it even harder to avoid stress, enjoy time with family, and finally return to work. Professor Helmut Zarbl, director at the Rutgers Environmental and Occupational Health Sciences Institute (EOHSI), […]