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In his Ph.D. study, Toni Luokkala investigated the soft tissue injuries related to elbow collateral ligaments and distal biceps tendon tears. The elbow is the second most commonly dislocated joint after the glenohumeral joint. The extent of soft tissue injuries has an effect on the choice of treatment, rehabilitation and prognosis. Instability of the elbow […]
Using similar technology to 3D printing, bioprinting uses a digital file as a blueprint to fabricate biomedical parts that closely imitate the characteristics of natural tissue. The engineered tissues are created by layering biomaterials and/or living cells, which are referred to collectively as bio-inks. Image Credit: Crevis / Shutterstock.com Bio-inks must possess certain physicochemical properties […]
Tissue oxygenation is a measure of the oxygen level in biological tissue and is a useful clinical biomarker for tissue viability. Abnormal levels may indicate the presence of conditions such as sepsis, diabetes, viral infection, or pulmonary disease, and effective monitoring is important for surgical guidance as well as medical care. Several techniques exist for […]
Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor’s healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can be life-saving, a major complication is the development of graft-versus-host disease (GVHD), which causes significant morbidity and can be fatal. Before allogenic […]
The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival. For microscopical analysis, full tissue samples provide a better picture of the immune cell activity in the tumor compared to tissue-sparing punch biopsies. A team led by the visceral surgeon Elisabeth S. Gruber and […]
On 6 March at 11:50 p.m. EST, the International Space Station resupply mission Space X CRS-20 took off from Cape Canaveral (U.S.). On board were 250 test tubes from the University of Zurich containing adult human stem cells. These stem cells will develop into bone, cartilage and other organs during the month-long stay in space. […]
A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer conventional course of treatment. Sarcoma, a rare type of cancer of the soft tissues (for example, […]
Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix. Until today, the question about the exact anatomical origin of these fibroblasts has not been answered. In order to find potential ways […]
A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response. The study was published today in Nature Communications. The researchers created models that include brain-derived extracellular matrix (ECM) […]
Cancer cells may ‘corrupt’ surrounding healthy tissue to help tumours grow, spread and resist treatment, scientists claim Scientists studied the tissue that surrounds mice tumours in the laboratory Cancer ‘exerts a powerful influence over its neighbouring cells’ Helps experts understand how tumours trigger changes that help them survive Cancer cells may ‘corrupt’ healthy tissue to help them […]