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Vitamin B12 is required for the proper function and development of the brain, nerves, blood cells, and many other parts of the body. The nutrient’s contribution is easily overlooked if you are getting enough of it, however, taking too much of it can create a dire effect on your health. What do you need to […]
Senescence is a response to cell damage and stress characterized by the arrest of the cell cycle. When aging, cells permanently stop dividing, thus preventing the propagation of damaged and dysfunctional cells. However, eventually, a massive quantity of senescent cells accumulate in tissues, resulting in the onset and progression of multiple disorders, including diabetes, cardiovascular […]
Emerging cancer nanotechnology enables targeted delivery of drug payloads to cancer sites with concomitant reduction of side effects due to reduced accumulation in critical organs. This prompts research into nanocarriers of therapeutic cargo and contrast agents, allowing combined cancer therapy and tumour visualization, respectively. Researchers from Lobachevsky University of Nizhny Novgorod, Russia, have implemented such […]
Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure. University of Alabama at Birmingham researchers now describe an important contributor to that heart pathology—disruption of the metabolism that […]