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Patients diagnosed with pancreatic cancer face a poor prognosis because the tumor forms dense scar-like tissue that is difficult for chemotherapy drugs to penetrate, but a new model may help researchers develop new therapies. “More than 85 percent of pancreatic tumors form this fibrous tissue,” explained Assistant Professor Joshua Reineke of the South Dakota State […]
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gene expression and enhanced anti-cancer immunity. It is the first time this particular kinase has been linked to gene silencing in mammals. Jean-Pierre Issa, MD, Director of the Fels Institute […]
Parents beg officials to approve the life-saving £450,000 drug which can treat the rare condition crippling their five-year-old son Finley Newell, from Haddenham, Buckinghamshire, has spinal muscular atrophy A drug already exists which could improve his life but the NHS can’t buy it In August regulators said the £450,000 drug was not value for money […]
‘Just as everyone’s spots were clearing up, mine became worse’: Woman, 28, who had perfect skin throughout her teenage years is left with a permanently scarred face after developing severe acne in her TWENTIES Emilie Love first developed minor breaks outs when she was 16 years old Years later, her blemishes turned into cystic acne […]
Pin Look, we know sugar — especially the refined sugar in candy — isn’t good for us. And sure, we try to avoid it whenever possible… but what about Halloween? Is it really that bad to let kids indulge like this once a year? To answer this question, we turned to the professionals who deal […]
Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss. Therapies targeting a specific cytokine, vascular endothelial growth factor (VEGF), have transformed clinical care; however, not all patients respond well. A new report in […]
The tiny tickler that can banish snoring and treat sleep apnoea Revealed: The tiny tickler that can banish snoring and treat sleep apnoea An implant in the chest that delivers tiny impulses of electricity may provide a new way to tackle sleep problems. The device has been developed to treat sleep apnoea, which is characterised […]
(HealthDay)— Only about half the parents of asthmatic preschoolers had the right knowledge and medicines on hand to treat their child’s breathing condition at home, a new study found. And one-third of those children had empty inhalers, the researchers reported. “The inability to treat asthma could lead to emergency department visits,” explained senior study author […]
Chemotherapy breakthrough: ‘Microbubbles’ loaded with drugs could destroy more than half of hard-to-treat tumours without any side effects Destroy 60% of hard-to-treat cancers, such as breast and lung, in mice Therapy only targets immune cells that work to fight off tumours Therefore avoids the side effects of treating all cells, like inflammation Means drugs could […]