Researchers from Singapore and South Korea have uncovered new details of a brain pathway that can cause impulsive behaviours. Using mice, the research team led by Professor George Augustine from Nanyang Technological University, Singapore (NTU Singapore), discovered that impulsive behaviour is triggered when the brain signalling chemical dopamine is passed to an unexpected area of […]
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Scientists discover Ebola virus in West African bat
The government of Liberia, in partnership with the Center for Infection and Immunity (CII) at the Columbia University Mailman School of Public Health and EcoHealth Alliance, announced the discovery of Ebola virus in a bat in Liberia. This is the first finding of Zaire ebolavirus in a bat in West Africa, adding to other evidence […]
New treatment approach for leukemia
The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia. The gene causes white blood cells to become leukemia cells that reproduce out of control. Earlier studies by the research group of Veronika Sexl at Vetmeduni Vienna had already […]
Research raises hope for new therapies for chordoma, a rare bone cancer
Chordoma is literally a one in a million cancer, with few effective treatment options. A new understanding of the biology behind this tumor type is bringing novel opportunities to light. A partnership pairing scientists from several research centers and a nonprofit organization dedicated to a rare cancer is starting to bear fruit, according to a […]
Researchers discover new biomarker for age-related macular degeneration
Researchers from the University of Alabama at Birmingham Department of Ophthalmology and Visual Sciences, along with collaborators from the University of Iowa, have discovered a genetic biomarker that is associated with age-related macular degeneration and delayed rod-mediated dark adaptation—the first visual function for incident AMD in older adults with normal macular health and early AMD. […]
Overprescribing of antidepressant medications may be common in elderly patients
In a Pharmacology Research & Perspectives study of individuals living in Olmsted County, Minnesota from 2005-2012, potential overprescribing of antidepressant medications occurred in nearly one-quarter of elderly residents. Potential antidepressant overprescribing was most likely in individuals residing in nursing homes; patients having a higher number of comorbid medical conditions; individuals who were outpatients; those taking […]
Cigarette smoking associated with increased risk of peripheral artery disease in African-Americans
African Americans who smoke cigarettes are more likely than those who don’t smoke to develop peripheral artery disease, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. Peripheral artery disease (PAD) is a narrowing of arteries other then those directly serving the […]
Stressed? Having a partner present—even in your mind—may keep blood pressure down
When faced with a stressful situation, thinking about your romantic partner may help keep your blood pressure under control just as effectively as actually having your significant other in the room with you, according to a new study by University of Arizona psychologists. For the study, published in the journal Psychophysiology, 102 participants were asked […]
Supplement makes (mouse) moms’ milk better; pups benefit for life
Giving mouse moms a supplement called nicotinamide riboside (NR) while they are nursing provides physical and behavioral benefits to both mothers and pups, according to a new study by researchers at the University of Iowa. Mother mice given the NR supplement lost weight faster and produced more milk than mothers not fed NR. In addition […]
Faulty molecular master switch may contribute to AMD
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have found that interrupting TGF-beta signals to immune cells called microglia causes the cells to enter an activated, inflammatory state. […]