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Depression: No protective effect by Vitamin-D supplements

Supplement with Vitamin D does not reduce the risk of Depression in adults. This was the result of the largest study of the topic. In recent years, has often been reported of a possible protective effect against depression.

Researchers from the Massachusetts General hospital and Harvard Medical School found in a large study, there was no evidence to suggest that Vitamin D supplements reduce the risk of Depression. In addition, no improvement in the General mood by these preparations could be demonstrated. The results were presented in the prestigious journal “JAMA”.

No Benefit from Vitamin-D-pills for depression

It has long been suspected that Vitamin can protect D-additions from depression. The largest studies of this kind, however, to the conclusion that this is not the case. “There was no significant Benefit of supplementation for this purpose,” concludes the research team on the basis of their analyses. Vitamin-D-ergänuzung medium can be prevented, therefore, neither depression, nor in these depression help, underlining the main author Olivia I. Okereke of the psychiatric Department of the Massachusetts General Hospital.

No difference to Placebo

The findings are based on data from over 18,000 men and women in the middle ages. Half of the Participants received Vitamin D3 supplementation over an average period of five years. The other half took, instead, a Placebo medication over the same period.

The results were clear. Under the 18.353 randomized Participants, the Team found that the risk of Depression or clinically relevant depressive symptoms between those who received Vitamin D3 supplements and those who received a Placebo, the difference was not significant. Likewise, no significant differences between the treatment groups in the sentiment values over time could be detected.

Previous studies were too small

“It’s a scientific Problem consists in the fact that one actually needs a very large number of study participants to say whether a treatment is helping to prevent the development of a Depression or not,” explains Okereke. The current study was hedged with almost 20,000 people, statistically, to address this Problem.

Reason for taking is crucial

“Vitamin D is known that it is for bone health and metabolism is essential, but randomized studies have many of the other suspected benefits in doubt,” says the lead author. The brightening of the mood, the preparations can not be recommended from a medical point of view. In the case of a diagnosed Vitamin D deficiency, the supplements were useful. (vb)

Also read: Vitamin D supplements is useless and more risky.

Authors and source of information