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A sedentary lifestyle can cause an impairment of the transport of blood around the body, which increases the risk of disease in the heart and blood vessels. New research published in Experimental Physiology suggests that performing simple leg exercises whilst lying down might help to prevent these problems. Previous work has demonstrated that prolonged sitting […]
Today, diagnosing rare genetic diseases requires a slow process of educated guesswork. Gill Bejerano, Ph.D., associate professor of developmental biology and of computer science at Stanford, is working to speed it up. In a paper published July 12 in Genetics in Medicine, Bejerano and his colleagues describe an algorithm they’ve developed that automates the most […]
Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Where the T-cells go has been unclear, even as immunotherapies are increasingly employed to stimulate the body’s natural ability to fight invasive tumors. Now researchers […]
MIT researchers are employing novel machine-learning techniques to improve the quality of life for patients by reducing toxic chemotherapy and radiotherapy dosing for glioblastoma, the most aggressive form of brain cancer. Glioblastoma is a malignant tumor that appears in the brain or spinal cord, and prognosis for adults is no more than five years. Patients […]
Investigators have discovered that arsenic in combination with an existing leukemia drug work together to target a master cancer regulator. The team, led by researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC), is hopeful that the discovery could lead to new treatment strategies for diverse types of cancer. Their findings were […]
The Centers for Disease Control and Prevention (CDC) released a report earlier this year on the increase of tick-, flea- and mosquito-borne illnesses in the United States, but don’t panic. Kurt Vandegrift, assistant research professor of biology at Penn State, works on emerging infectious diseases, and his lab studies ticks. Vandegrift’s lab is part of a National […]
(HealthDay)—Young pregnant women who are obese may face a higher risk of changes in heart structure and function, a small new study suggests. The changes seen might lead to a pregnancy complication known as preeclampsia, according to the researchers. This disorder is a dangerous form of high blood pressure that can develop during the second […]
Premature birth alters the balance of interneurons in the cerebral cortex that can be restored with estrogen treatment, according to a study of human brain tissue and preterm rabbits published in JNeurosci. Infants born prior to a full-term pregnancy are at increased risk of neurobehavioral disorders linked to defects in interneurons, which continue to develop […]
Scientists from the University at Buffalo in New York find that the receptor muscarinic type 3 (M3R) is a “key regulator” of remyelination, which is the process that replenishes lost myelin. M3R is found on the surface of oligodendrocyte progenitor cells (OPCs), the precursors to the cells that make myelin. A receptor is a cell-surface […]
Scientists have found that it is the structure of collagen, rather than the amount, that leads to the devastating condition of lung fibrosis, according to a report in the journal eLife. The study provides the first evidence in humans that altered collagen structure affects tissue stiffness during progression of lung fibrosis and identifies a potential […]