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For over a century, researchers have known about “the bends”, a serious condition affecting scuba divers. However, we still know relatively little about its physiological basis. Doctors do not yet have a definitive test for the bends, instead relying on symptoms to diagnose it. A new study in Frontiers in Physiology is the first to […]
A retrospective study conducted by scientists from the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna General Hospital found that compiling a tumor molecular profile can result in better risk stratification and hence to better treatment decisions in endometrial cancer. The use of so-called “integrated molecular risk classification” could reduce the use of chemo- […]
Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease (LOAD), as well as a promising therapeutic candidate for treatment, according to a study in the journal Neuron. LOAD is the most prevalent form of dementia among people over age 65, a […]
A new deep-learning algorithm can quickly and accurately analyze several types of genomic data from colorectal tumors for more accurate classification, which could help improve diagnosis and related treatment options, according to new research published in the journal Life Science Alliance. Colorectal tumors are extremely varied in how they develop, require different drugs and have […]
Researchers have mapped out some of the mechanisms that may affect women’s fertility from the teenage years to menopause. These mechanisms largely depend on naturally occurring chromosome errors—errors that vary depending on age group. This is the conclusion by an international research group in a new study, led by researchers from the University of Copenhagen. […]
Current anti-cancer drugs can be quite effective but too often, tumors are not fought off completely and end up returning. A recent study published in The FASEB Journal provides the first evidence that some cancer cells evade therapy by switching over to alternative molecular mechanisms that are not affected by existing anti-cancer treatments. A research […]
In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive protein modification that spurs on Alzheimer’s disease. “Roughly ten percent of Alzheimer’s disease cases are the result of identified […]
Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat. In a paper published in the journal Circulation Research, they used this technique to uncover the effects of genetic errors that contribute to […]
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have found that interrupting TGF-beta signals to immune cells called microglia causes the cells to enter an activated, inflammatory state. […]
Becoming overweight at a young age can trigger a molecular chain reaction that leads some girls to experience puberty early, according to new research published in Nature Communications. Scientists have discovered a molecular mechanism that leads overweight female rats to have early-onset puberty. “Knowing how nutrition and specific molecules play a role in starting puberty […]