Health Problems

What is a Polybasic Cleavage Site?

The polybasic cleavage site is a proteolytic excision site utilized by cellular proteases that activate a wide range of precursor proteins. The acquisition of a polybasic cleavage site is associated with viral pathogenicity and virulence. Image Credit: ibreakstock/Shutterstock.com What is a polybasic cleavage site? Proteolytic excision at polybasic cleavage sites is a post-translational modification phenomenon […]