Health News

Fragmenting ions and radiation sensitizers

A new study using mass spectrometry is helping piece together what happens when DNA that has been sensitized by the oncology drug 5-fluorouracil is subjected to the ionising radiation used in radiotherapy. The anti-cancer drug 5-fluorouracil (5FU) acts as a radiosensitizer: it is rapidly taken up into the DNA of cancer cells, making the cells […]

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Killing the seeds of cancer: A new finding shows potential in destroying cancer stem cells: The finding could provide an important step toward drugs that help prevent recurrent cancers

Scientists at The University of Toledo investigating improvements to a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells. Their findings could prove to be a breakthrough in not only treating tumors, but ensuring cancer doesn’t return years later — giving peace of […]

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Molecular chatter makes for a ‘hot tumor’

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells. “We show that two key chemokines, CCL5 and CXCL9, are universally implicated in T cell infiltration across all solid tumors,” said George […]

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Protein that hinders advancement of prostate cancer identified

Researchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer (CRPC). Under the direction of BUSM’s Gerald V. Denis PhD, researchers have long studied a family of three closely related proteins, called BET bromodomain proteins, composed of […]