Health News

Gene could slow down tumor repair in breast cancer brain metastasis

Treating tumors presents a tricky conundrum: a higher dose of radiation is more effective for treatment, but the higher the dose, the more danger it poses to healthy cells. Researchers at Yale have made significant inroads into solving this problem in a paper titled, “LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to […]

Health News

Induced liver regeneration enhances CRISPR/Cas9-mediated gene repair

Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This dietary induction of hepatocyte regeneration may be a viable clinical strategy to enhance gene repair in the liver, according to the peer-reviewed journal Human Gene Therapy. The study was done in a mouse model of […]

Health News

DNA repair supports brain cognitive development

It’s a fact of life that things break down. And when they do, whether it’s your car, the roof, or a blocked artery, there are people who we can call to help with the repairs. A lesser known fact of life is that DNA also regularly breaks down and needs to be repaired. Researchers led […]

Health Problems

RUNX proteins act as regulators in DNA repair, study finds

A study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia (FA) pathway. Led by Professor Yoshiaki Ito, Senior Principal Investigator at CSI Singapore, and involving Senior Research Scientist Dr. Vaidehi Krishnan […]