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Skip to: What is Testosterone Replacement Therapy? What are the Benefits of TRT? What are the Risks of TRT? Testosterone plays a vital role in the human body. Its effects increase muscle and bone strength and density, induce hematopoiesis, and drive libido and sexual function. Testicular production of testosterone typically declines with age, which can […]
Skip to: What are tumorspheres? Tumorsphere formation assay Technical notes on tumorsphere cultivation What are the types of cancer stem cell (CSC) tumorspheres? Tumorspheres for screening anti-CSC drugs What is the future of tumorspheres? What are tumorspheres? Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, […]
Patients in a coma are described as being in a state of unconsciousness from which they cannot be woken and are unresponsive. Typical causes of coma include stroke, seizures, severe head injury, infection of the brain such as encephalitis, or alcohol poisoning. Those with diabetes pose an additional risk of falling into a coma if […]
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry enables rapid profiling of various biomolecules from both tissues and biofluids. Rost9 | Shutterstock Although MALDI was originally used for the analysis of peptides and proteins, it now plays an important role in biomarker discovery, genotyping, identification of microorganisms, lipidomic analysis, and metabolomics. Improvements in the selection of […]
Skip to: What is arthritis? The impact of lack of sleep The effect that lack of sleep can have on arthritis The chronic pain associated with arthritis is well known to negatively impact sleep. However, recent research has implied that a lack of sleep and insomnia can themselves can adversely affect arthritis symptoms. What is […]
Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects one in 10 Americans. The article, “RIPK3-mediated inflammation is a conserved β-cell response to ER stress” was published in the journal Science Advances on […]
An international research team led by the University of British Columbia (UBC) has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women. The organ in question is the thymus, identified in a study published today in the journal Nature […]
Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature. The World Health Organization (WHO) has declared AMR as one of the top 10 global public […]
Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women. This finding, which examined blood specimens from the landmark Women’s Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens […]