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The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has largely defied attempts to contain its spread by non-pharmaceutical interventions (NPIs). With the massive loss of life and economic damage, the only way out, in the absence of specific antiviral therapeutics, has been the development of […]
Back in 1892, Doderlein first established the beneficial association of microorganisms in the human body. Therefore, under the COVID-19 pandemic, it can be beneficial to assess microorganisms' role in the human body and the use of probiotics as therapy for COVID-19 patients. While the term "microbiome" (coined by the Nobel laureate Joshua Lederberg, 2001) includes […]
Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects one in 10 Americans. The article, “RIPK3-mediated inflammation is a conserved β-cell response to ER stress” was published in the journal Science Advances on […]
A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists in the journal Cell. Their findings suggest new therapies should disable Ebola virus’s infection machinery and spark the patient’s immune system to call in reinforcements. “This study presents results from an unprecedented international collaboration […]