Health News

Antibiotic Therapy Before Age 2 May Affect Child Health

TUESDAY, Nov. 17, 2020 — Exposure to antibiotics in the first two years of life is associated with an increased risk for several health conditions during childhood, according to a study published online Nov. 15 in the Mayo Clinic Proceedings. Zaira Aversa, M.D., Ph.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a […]

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Is proton therapy the silver bullet for children with brain cancer?

Adelaide is poised to open Australia’s first proton therapy center in 2025, with children and young adults expected to be the main beneficiaries of more effective cancer treatment with fewer side effects. But just how safe is proton therapy for children with brain cancer compared to the conventional X-ray radiation delivered post-surgery? A new study […]

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Biologic therapy for psoriasis may reduce heart disease

Patients with psoriasis treated with biologic therapy, which are protein-based infusions to suppress inflammation, had a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research published today in Circulation: Cardiovascular Imaging, an American Heart Association journal. Chronic inflammation in people with psoriasis is associated with a higher risk of developing […]

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Getting gene therapy to the brain

A lone genetic mutation can cause a life-changing disorder with effects on multiple body systems. Lysosomal storage diseases, for example, of which there are dozens, arise due to single mutations that affect production of critical enzymes required to metabolize large molecules in cells. These disorders affect multiple organs including, notably, the brain, causing intellectual disability […]

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Artificial RNA editing with ADAR for gene therapy

Many of the diseases caused by point mutations have no established therapeutic approaches. Prof. Tsukahara and colleagues (Japan Advanced Institute of Science and Technology) are studying a therapeutic method using artificial RNA editing. Artificial site-directed RNA editing is an important technique for modifying genes and ultimately regulating protein function. We are trying to modify the […]

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Precision medicine guides choice of better drug therapy in severe heart disease

Is personalized medicine cost-effective? University of Alabama at Birmingham researcher Nita Limdi, Pharm.D., Ph.D., and colleagues across the United States have answered that question for one medical treatment. Patients experiencing a heart attack—known as a myocardial infarction or an acute coronary syndrome—have sharply diminished blood flow in coronary arteries, with a high risk of heart […]