Health News

Transporter’s role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction and chronic infections. To explore the cellular and molecular mechanisms underlying the role of NKCC1 in the intestinal pathology, Eric Delpire, Ph.D., and […]