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Crohn’s disease and ulcerative colitis, chronic autoimmune disorders collectively known as inflammatory bowel disease (IBD), affect about 3 million Americans. They require a significant amount of medical management, sometimes including immunosuppressant medications with potentially scary side effects. What’s more, people with IBD often feel shame about their condition because of its connection to bathroom behaviors, […]
Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut. A defective intestinal TJ barrier, sometimes known as “leaky gut,” plays an important role in exacerbating and prolonging intestinal inflammation. New research reported in […]
Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut. A defective intestinal TJ barrier, sometimes known as “leaky gut,” plays an important role in exacerbating and prolonging intestinal inflammation. New research reported in […]
If you frequently suffer from migraines, you know how debilitating they can be. But figuring out how to treat them doesn’t need to be another pain in the head; while there are all kinds of myths and pseudoscience remedies out there on the internet (like daith piercings, which haven’t actually been proven to be effective), […]
One third (35%) of people who took a new drug for treating obesity lost more than one-fifth (greater than or equal to 20%) of their total body weight, according to a major global study involving UCL researchers. The findings from the large-scale international trial, published today in the New England Journal for Medicine, are being […]
A new study, published in Diabetologia, presents the results of the largest clinical trial for diabetic retinopathy. The study highlights a new approach that could transform diabetic eye screening around the world that also has a significant cost saving for the NHS. The number of people living with diabetes in the world is over 460 […]
As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges. One is intratumor heterogeneity—the presence of multiple kinds of cancer cells within the same tumor. Often, these “mosaic” tumors include cells, such as polyploidal giant cancer cells, that have evolved to become aggressive and resistant to chemotherapy […]
COVID-19 can be diagnosed several ways when looking for active infection. “The most common way that testing is done is with a swab into the nose or into the nasal pharyngeal area,” says Dr. Stacey Rizza, a Mayo Clinic infectious diseases expert. “This polymerase chain reaction (PCR) test is essentially a test looking for the […]
Huntington’s disease is a progressive and aggressively debilitating brain disorder that causes uncontrolled movements, psychological problems, and loss of cognition. It is caused by a mutation in the gene that encodes the protein huntingtin, causing it to build an abnormally long tail of the amino acid glutamine. This tail prevents huntingtin from folding properly and […]
As the number of COVID-19 patient records grows, researchers are meticulously combing through the data, searching for a better understanding of the virus and what we can expect in the months and years ahead. What is now of increasing concern in health care is the realization that the virus can not only be severe, but […]