Health Problems

Scientists create brain-mimicking environment to grow 3-D tissue models of brain tumors

A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response. The study was published today in Nature Communications. The researchers created models that include brain-derived extracellular matrix (ECM) […]

Health Problems

Identification of all types of germ cells tumors

Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or after puberty. The majority are benign. Malignant germ cell tumors most frequently appear in the testicle of adolescent and young adult men. Fortunately, […]

Health News

So our immune system also protects against colon cancer

Protection mechanism discovered: How the immune system protects against bowel cancer Again and again, it is pointed out how important it is to strengthen its defenses. A healthy immune system can fend off pathogens and diseases preserve. It may even protect against the most serious diseases such as colon cancer. One of the most common […]

Health Problems

New model mimics human tumors for accurate testing of cancer drugs

Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]

Health Problems

Tailored drug cocktails offer hope to kids with aggressive brain tumors

UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in which survival has plateaued for decades. In the trial, UCSF […]

Health Problems

Epigenetic analysis of aggressive brain tumors

Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than three years. Many efforts to develop new, targeted treatments have failed over the last […]