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Frontline CLL Therapy: Avoiding Adverse Events
NEW YORK – The Food and Drug Administration’s 2016 approval of the Bruton’s tyrosine kinase inhibitor ibrutinib (IB) as a frontline therapy for chronic lymphocytic leukemia (CLL) dramatically improved overall survival rates for patients with this condition. Follow-up data from 8 years after the RESONATE-2 trial indicated that patients with CLL (65 years or older) who remain on […]
The potential anti-cancer and antioxidant properties of walnuts
In a recent study published in the journal Antioxidants, researchers reviewed current literature to examine walnuts' potential antioxidant and anti-cancer properties and the health benefits of incorporating walnuts into the diet. Study: Antioxidant and Anti-Inflammatory Properties of Walnut Constituents: Focus on Personalized Cancer Prevention and the Microbiome. Image Credit: SOMMAI/Shutterstock.com Background An essential part of the Mediterranean […]
RFID tagging technology streamlines cryogenic sample management
Ziath, a Azenta Life Sciences company, announce a revolution in cryogenic sample management – the Ri-Track Mirage 2D barcoded tube whole rack reader. Image Credit: Ziath Traditionally identifying the identity of frost covered racks of 2D barcoded tubes taken from low temperature storage has been a time-consuming and error prone process. Drawing upon proprietary Radio Frequency […]
Novel treatment regimen appears well tolerated, beneficial to children with relapsed brain tumors
The first in-human-study of a new immunotherapy that blocks a natural enzyme tumors commandeer for their protection was well tolerated by children with relapsed brain tumors and enabled many to have unexpected months of a more normal life, researchers say. “Our kids were by and large out of the hospital and going about their daily […]
A genetic mutation found to cause chronic lung disease in indigenous children
Overcrowded housing, high rates of tobacco exposure, poor vaccination uptake and damage after severe respiratory infection in infancy: these are some of the reasons that are sometimes suggested to explain why indigenous children suffer more severe lung infections than other children in North America—with no conclusive proof. According to a team of scientists led by […]
No reduction in death or severe brain injury with cerebral oximetry monitoring in extremely preterm infants, finds study
An international team of 100 researchers at 70 sites in 17 countries has found no reduction in death for treatment guided by cerebral oximetry monitoring in extremely preterm infants. In the paper “Cerebral Oximetry Monitoring in Extremely Preterm Infants,” published in the New England Journal of Medicine, researchers report on the outcome of a phase […]
Problems with ‘pruning’ brain connections linked to adolescent mental health disorders
Problems with the brain’s ability to “prune” itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today. The findings, from an international collaboration, led by researchers in the U.K., China and Germany, may help explain why people are often affected by more than […]
Drug combination restores ability of leading treatment to signal for death of blood cancer cells
Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs’ effects within a year. Now, new research using human tissue samples and mouse models has found that resistance of leukemia cells to a widely prescribed drug called […]
Study finds sex differences in the healing process after a muscle injury
The time period in which muscles heal after injury may depend on biological sex, and applying personalized treatment may help optimize recovery, according to a new study. Researchers from Duquesne University in Pittsburgh will present their work this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society (APS), in […]