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Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should. By using new CRISPR/Cas9 genome editing technology, in a recent paper in Nature Communications, McGill University researchers have described a new technique that scientists across the world can potentially […]
(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Kristina A. Theis, Ph.D., from the CDC in Atlanta, and colleagues analyzed combined National Health Interview Survey data from 2016 to 2018 to update national […]
Millions of people suffer from psoriasis, a chronic, autoimmune disorder that causes scaly patches on the skin and often precedes psoriatic arthritis. While no cure exists, treatments range from topical creams to injected medications that block inflammation. To improve treatment options, scientists need to better understand the dysregulation of the immune system that leads to […]
New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the body’s own joint tissues. Published in the journal Arthritis & Rheumatology, the discovery could […]
TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and development of collagen-induced arthritis (CIA) was notably […]
Editor’s note: The original text has been revised and updated. As Gavin Giovannoni, MBBCh, PhD, an esteemed British multiple sclerosis (MS) expert, set out for his Saturday morning run on Nov. 7, 2020, the world’s weighty problems swirled through his head. Brexit, a U.S. election, a global pandemic, not to mention the daily struggles of […]
Skip to: What is arthritis? The impact of lack of sleep The effect that lack of sleep can have on arthritis The chronic pain associated with arthritis is well known to negatively impact sleep. However, recent research has implied that a lack of sleep and insomnia can themselves can adversely affect arthritis symptoms. What is […]
(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in the International Journal of Rheumatic Diseases. Yeon-Kyung Lee, from the Hanyang University Hospital for Rheumatic Diseases in Seoul, South Korea, and colleagues examined the causes and risk for death in 2,355 […]
A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center (VUMC). The researchers demonstrated that the drug abatacept reduced the severity […]
A pioneering study carried out among patients in remission from Rheumatoid Arthritis has determined that they display significantly higher temperatures than healthy individuals. The work, published in PLOSONE and undertaken by University of Malta and Staffordshire University, compares thermographic patterns of patients with Rheumatoid Arthritis (RA) in remission with healthy individuals. More than 31 RA […]