Research suggests lowering blood pressure significantly reduces dementia risk in people with hypertension

The average blood pressure in the intervention group at 48 months was 128/73 mm Hg, compared to 148/81 mm Hg in the usual care group.
On average, systolic blood pressure decreased by 22 mm Hg and diastolic blood pressure decreased by 9 mm Hg among people in the intervention group compared to usual care.
People in the intervention group had 15% lower risk of dementia and 16% lower risk of memory impairment compared to the group that received usual care.
Serious adverse events, such as hospitalizations and death from all causes, were also less frequent in the intervention group.

The trial began in May 2018 and ended in March 2023.
The average age of study participants at enrollment was 63 years old. 61% identified as women, and 39% identified as men; researchers observed similar reductions in blood pressure and dementia risk in women and men.