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A new study by De, Agrawal, Morrone et al, chal-lenges the common notion that airway inflammation in Sickle Cell Disease (SCD) is secondary to asthma, even though the two disorders often coexist. In a recent pilot, cross sectional study, both systemic and airway inflammatory markers were compared in patients with sickle cell disease with and […]
Contrary to popular belief, there may be more than one mechanism involved in microbial airway protection. Researchers from Japan and China have found an alternative mechanism that may be involved in fighting microbial infections. The inflammation pathway in response to microbial infections involves multiprotein complexes known as inflammasomes. It is known that inflammasomes induce inflammation […]